![]() ![]() In rare occurrences when there is no functional protein name, the format “protein ” may be used, not “ protein”.ĭ.melanogaster: tyrosine-protein kinase Abl In the case of conserved genes, if there is no known gene symbol in use in the species already, a known orthologous gene symbol from a species where the symbol was originally defined may be used. For non-vertebrate eukaryotes, follow the gene casing conventions of the species in question. For vertebrates, use an all uppercase gene symbol in a protein name. In rare occurrences when there is no functional protein name, the format "protein " may be used, not " protein".Ī gene symbol is commonly used in eukaryote protein names in combination with a functional protein name.Ĭapitalization conventions of gene symbols differ between organism communities and this is reflected in the casing of gene symbols used as part of eukaryotic protein names. The first letter of a protein symbol is capitalized for prokaryotes e.g. Some gene and protein symbols are easily recognized by database users in certain research communities and can be used as part of a protein name to provide specification and aid data retrieval.Ī protein symbol is most commonly used in prokaryote protein names in combination with a functional protein name. Protein and gene symbols should use the same abbreviation. Protein name based on a protein symbol (PS) or gene symbol (GS) See below for a list of standard scientific abbreviations. avoid names such as ‘protein IMPACT’.Ĭheck if the proposed name for a newly discovered protein is already used for a different protein.Īvoid using an abbreviation as the complete nameĪn abbreviation may be part of a protein nameĮxample: (3R)-hydroxymyristoyl-ACP dehydratase Use protein names ending in 'in' (not 'ine')Īvoid diacritics such as accents, umlauts etc.Įxample: protein spatzle 5 not protein spätzle 5Īvoid pluralization for names based on domain and repeat contentĮxample: ankyrin repeat-containing protein not ankyrin repeats-containing proteinĪvoid naming proteins with common words which makes querying difficult e.g. Uncharacterized protein not uncharacterised protein Use American spelling, not British spelling This does not include best practices on methods to be used for sequence function identification/prediction. This document provides guidelines on naming choices and universal formatting. The process of associating a name with a protein sequence has various components: sequence function identification/prediction, choosing a name and applying formatting. ![]() A good protein name is one which is unique, unambiguous, can be attributed to orthologs from other species and follows official gene nomenclature where applicable. Consistent protein nomenclature is indispensable for communication, literature searching and entry retrieval.
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